Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.

Microbiology (Reading, England) - 1 May 2009

Hendriksen Wouter T, Bootsma Hester J, van Diepen Angela, Estevão Silvia, Kuipers Oscar P, de Groot Ronald, Hermans Peter W M

Abstract excerpt

Previous studies have indicated that PsaR of Streptococcus pneumoniae is a manganese-dependent regulator, negatively affecting the expression of at least seven genes. Here, we extended these observations by transcriptome and proteome analysis of psaR mutants in strains D39 and TIGR4. The microarray analysis identified three shared PsaR targets: the psa operon, pcpA and prtA. In addition, we found 31 genes to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pneumonia, Pneumococcal

Share to Species Specificity

Share to Streptococcus pneumoniae

Share to Transcription Factors

Share to Virulence

Source

Identifiers

PMID: 19372167
DOI: 10.1099/mic.0.025072-0

Genes

PTS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.PMID 19372167Read ↗

Pneumococcal metabolic adaptation and colonization is regulated by the two-component regulatory system 08Semantic proximity Read ↗

Regulation of gene expression in Streptococcus pneumoniae by response regulator 09 is strain dependent.Semantic proximity Read ↗

Effects of the ERES pathogenicity region regulator Ralp3 on Streptococcus pyogenes serotype M49 virulence factor expression.Semantic proximity Read ↗

Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors.Semantic proximity Read ↗

A two-component system that controls the expression of pneumococcal surface antigen A (PsaA) and regulates virulence and resistance to oxidative stress in Streptococcus pneumoniae.Semantic proximity Read ↗

Virulence factors in pneumococcal respiratory pathogenesis.Semantic proximity Read ↗

Genetic analysis of virulence of Streptococcus pneumoniaeSemantic proximity Read ↗

The core promoter of the capsule operon of Streptococcus pneumoniae is necessary for colonization and invasive disease.Semantic proximity Read ↗

LacR and TrxB are key virulence factors involved in pneumococcal meningitis as identified by a genome-wide association studySemantic proximity Read ↗

Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling.Semantic proximity Read ↗

Roles of <i>rel</i><sub><i>Spn</i></sub> in stringent response, global regulation and virulence of serotype 2 <i>Streptococcus pneumoniae</i> D39Semantic proximity Read ↗

An in vivo atlas of host-pathogen transcriptomes during Streptococcus pneumoniae colonization and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.