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Article

The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability.

The Journal of clinical endocrinology and metabolism - 1 Jul 2009

Vargiolu Manuela, Fusco Daniela, Kurelac Ivana, Dirnberger Dietmar, Baumeister Ralf, Morra Isabella, Melcarne Antonio, Rimondini Roberto, Romeo Giovanni, Bonora Elena

Abstract excerpt

CONTEXT: RET is a tyrosine kinase transmembrane receptor expressed in two main alternative isoforms: RET9 and RET51. RET transduces a positive signal leading to survival, differentiation, or migration in the presence of its ligand glial cell line-derived neurotrophic factor, whereas in its absence a proapoptotic fragment that initiates a negative signaling for apoptosis is generated. The signal transduction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19366855
DOI: 10.1210/jc.2008-1980

Genes

RET
AIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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