Article
A method for the generation of ectromelia virus (ECTV) recombinants: in vivo analysis of ECTV vCD30 deletion mutants.
PloS one - 1 Jan 2009
Alejo Ali, Saraiva Margarida, Ruiz-Argüello Maria Begoña, Viejo-Borbolla Abel, de Marco Mar Fernández, Salguero Francisco Javier, Alcami Antonio
Abstract excerpt
BACKGROUND: Ectromelia virus (ECTV) is the causative agent of mousepox, a lethal disease of mice with similarities to human smallpox. Mousepox progression involves replication at the initial site of infection, usually the skin, followed by a rapid spread to the secondary replicative organs, spleen and liver, and finally a dissemination to the skin, where the typical rash associated with this and other...
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