Article
Structural determinants of chemokine binding by an Ectromelia virus-encoded decoy receptor.
Journal of virology - 1 Aug 2006
Arnold Phoebe L, Fremont Daved H
Abstract excerpt
The EVM1 protein encoded by Ectromelia virus is a member of a highly conserved family of poxvirus chemokine binding proteins that interfere with host immune surveillance processes. EVM1 is abundantly expressed early during mousepox infection and is able to selectively bind CC chemokines and inhibit their interactions with host receptors. Here, we characterize the interaction between EVM1 and the human and murine...
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