Evidence that the Agr‐like quorum sensing system regulates the toxin production, cytotoxicity and pathogenicity of <i>Clostridium perfringens</i> type C isolate CN3685

Abstract excerpt

Clostridium perfringens possesses at least two functional quorum sensing (QS) systems, i.e. an Agr-like system and a LuxS-dependent AI-2 system. Both of those QS systems can reportedly control in vitro toxin production by C. perfringens but their importance for virulence has not been evaluated. Therefore, the current study assessed whether these QS systems might regulate the pathogenicity of CN3685, a C....

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