Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia.

doi:10.1093/hmg/ddp166

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Article

Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia.

Human molecular genetics - 1 Jul 2009

Koga Minori, Ishiguro Hiroki, Yazaki Saori, Horiuchi Yasue, Arai Makoto, Niizato Kazuhiro, Iritani Shuji, Itokawa Masanari, Inada Toshiya, Iwata Nakao, Ozaki Norio, Ujike Hiroshi, Kunugi Hiroshi, Sasaki Tsukasa, Takahashi Makoto, Watanabe Yuichiro, Someya Toshiyuki, Kakita Akiyoshi, Takahashi Hitoshi, Nawa Hiroyuki, Muchardt Christian, Yaniv Moshe, Arinami Tadao

Abstract excerpt

Chromatin remodeling may play a role in the neurobiology of schizophrenia and the process, therefore, may be considered as a therapeutic target. The SMARCA2 gene encodes BRM in the SWI/SNF chromatin-remodeling complex, and associations of single nucleotide polymorphisms (SNPs) to schizophrenia were found in two linkage disequilibrium blocks in the SMARCA2 gene after screening of 11 883 SNPs (rs2296212; overall...

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PMID: 19363039
DOI: 10.1093/hmg/ddp166

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SMARCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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