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Article

Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.

Gastroenterology - 1 Jul 2009

Moriwaki Kenta, Noda Katsuhisa, Furukawa Yoichi, Ohshima Kenji, Uchiyama Airi, Nakagawa Tsutomu, Taniguchi Naoyuki, Daigo Yataro, Nakamura Yusuke, Hayashi Norio, Miyoshi Eiji

Abstract excerpt

BACKGROUND & AIMS: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes apoptosis in cancer cells, but not normal cells, and is critically involved in tumor rejection through natural killer (NK) cell-mediated immune surveillance. Oligosaccharides are involved in various aspects in carcinogenesis, and fucosylation is one of the most important oligosaccharide modifications in cancer. Here, we...

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Source

Identifiers

PMID: 19361506
DOI: 10.1053/j.gastro.2009.04.002

Genes

GMDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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