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Article

Superoxide anion regulates the mitochondrial free Ca2+ through uncoupling proteins.

Antioxidants & redox signaling - 1 Aug 2009

Wu Zhaofei, Zhang Jie, Zhao Baolu

Abstract excerpt

Mitochondrial dysfunction, which is closely related to intracellular calcium overload and excessive free radicals, is an important cause of Alzheimer's disease (AD). However, molecular mechanisms of the mitochondrial Ca(2+) disregulation induced by oxidative stress in AD are still obscure. In an effort to gain a further understanding of this problem, we investigated the effects of superoxide anion, a primary free...

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Source

Identifiers

PMID: 19361273
DOI: 10.1089/ars.2009.2427

Genes

APP
UCP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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