Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uncoupling protein 1 affects the yeast mitoproteome and oxygen free radical production.

Free radical biology & medicine - 15 Jan 2006

Douette Pierre, Gerkens Pascal, Navet Rachel, Leprince Pierre, De Pauw Edwin, Sluse Francis E

Abstract excerpt

Uncoupling protein 1 (UCP1) is a mitochondrial inner membrane protein that dissipates the proton electrochemical gradient built up by the respiratory chain. Its activity is stimulated by free fatty acids and inhibited by purine nucleotides. Here we investigated how active and regulated recombinant UCP1 expressed in yeast at approximately 1 and approximately 10 microg/mg of total mitochondrial proteins induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrophoresis, Gel, Two-Dimensional
Share to Free Radicals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Transfer Techniques

Share to Ion Channels

Share to Mitochondrial Proteins

Share to Oxygen

Share to Proteomics

Share to Uncoupling Protein 1

Source

Identifiers

PMID: 16413412
DOI: 10.1016/j.freeradbiomed.2005.08.024

Genes

UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uncoupling protein 1 affects the yeast mitoproteome and oxygen free radical production.PMID 16413412Read ↗

Uncoupling Protein 2, in Vivo Distribution, Induction upon Oxidative Stress, and Evidence for Translational RegulationSemantic proximity Read ↗

Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes.Semantic proximity Read ↗

Overexpression of UCP1 in tobacco induces mitochondrial biogenesis and amplifies a broad stress response.Semantic proximity Read ↗

Uncoupling proteins: the issues from a biochemist point of view.Semantic proximity Read ↗

New aspects of mitochondrial Uncoupling Proteins (UCPs) and their roles in tumorigenesis.Semantic proximity Read ↗

UCP2, a mitochondrial protein regulated at multiple levels.Semantic proximity Read ↗

Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.Semantic proximity Read ↗

Deleterious role of superoxide dismutase in the mitochondrial intermembrane space.Semantic proximity Read ↗

Alteration of ROS homeostasis and decreased lifespan in S. cerevisiae elicited by deletion of the mitochondrial translocator FLX1.Semantic proximity Read ↗

Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function.Semantic proximity Read ↗

UCP1, the mitochondrial uncoupling protein of brown adipocyte: A personal contribution and a historical perspective.Semantic proximity Read ↗

Yeast biological networks unfold the interplay of antioxidants, genome and phenotype, and reveal a novel regulator of the oxidative stress response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.