Variants in TPH2 and ADARB1 genes in completed suicide from the Slovenian population - a follow-up to findings on attempted suicide in the Serbian population.

doi:10.1080/15622975.2026.2617200

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Variants in TPH2 and ADARB1 genes in completed suicide from the Slovenian population - a follow-up to findings on attempted suicide in the Serbian population.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Mar 2026

Karanović Jelena, Supej Špela, Šalamon Arčan Iris, Pantović-Stefanović Maja, Ivković Maja, Zupanc Tomaž, Savić-Pavićević Dušanka, Videtič Paska Alja

Abstract excerpt

INTRODUCTION: Suicidal behaviour, including completed suicide and attempted suicide, is affected by genetic factors, involving serotonergic system genes. TPH2 gene encodes tryptophan hydroxylase 2, rate-limiting brain serotonin synthetising enzyme whose pre-mRNAs are edited by ADAR enzymes, including ADARB1. TPH2 rs4290270 and ADARB1 rs9983925/rs4819035 variants have been previously implicated in suicide attempt...

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Tryptophan Hydroxylase

Violence

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PMID: 41578154
DOI: 10.1080/15622975.2026.2617200

Genes

ADARB1
TPH2
ADAR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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