Article
LRRK2 screening in a Canadian Parkinson's disease cohort.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Aug 2007
Grimes D A, Racacho L, Han F, Panisset M, Bulman D E
Abstract excerpt
BACKGROUND: Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) have become the most common known cause for developing Parkinson's disease. The frequency of mutations described in the literature varies widely depending on the population studied with most reports focusing only on screening for the most common G2019S mutation in exon 41. METHODS: In this study seven exons (19, 24, 25, 31, 35, 38, and 41) in...
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