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Mammosphere‐derived gene set predicts outcome in patients with ER‐positive breast cancer

27 Feb 2009

Abstract excerpt

Tumourigenic subpopulations with stem cell-like features have been identified in breast tumours and breast cancer cell lines. The hormone receptor status, molecular characteristics and clinical significance of these cells are still matters of debate. Enrichment for tumourigenic cells without the requirement of surface markers can be achieved by the in vitro mammosphere culture assay. Here we compared the hormone...

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PMID: 19353633
DOI: 10.1002/path.2544

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