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Mammospheres of hormonal receptor positive breast cancer diverge to triple-negative phenotype.

Breast (Edinburgh, Scotland) - 1 Apr 2018

Laranjo Mafalda, Carvalho Maria João, Costa Tânia, Alves André, Oliveira Rui Caetano, Casalta-Lopes João, Cordeiro Patrícia, Botas Filomena, Abrantes Ana Margarida, Paiva Artur, Oliveira Carlos, Botelho Maria Filomena

Abstract excerpt

OBJECTIVES: This study aimed to characterize mammospheres from hormonal receptor (HR) positive and triple-negative breast cancer (TNBC), hypothesizing a differential profile of CSC and differentiation markers, and a stemness enrichment when successive sphere forming-protocols are performed. METHODS: Breast cancer cells MCF-7 and HCC1806 were submitted to sphere-forming protocols. The first sphere generation (MS1)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29182983
DOI: 10.1016/j.breast.2017.11.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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