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Article

CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization.

Biochemical and biophysical research communications - 27 Mar 2009

Nardini Marco, Valente Carmen, Ricagno Stefano, Luini Alberto, Corda Daniela, Bolognesi Martino

Abstract excerpt

C-terminal binding proteins (CtBPs) are multi-functional proteins involved in nuclear transcriptional co-repression, Golgi membrane fission, and synaptic ribbon formation. Binding of NAD(H) to CtBPs promotes dimerization. CtBP dimers act as a scaffold for multimeric protein complex formation, thus bridging transcriptional repressors and their targets in the nucleus. Based on size-exclusion chromatography...

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PMID: 19351597
DOI: 10.1016/j.bbrc.2009.02.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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