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Article

The effect of the levonorgestrel-releasing intrauterine system on the resistance to activated protein C (APC).

Thrombosis and haemostasis - 1 Apr 2009

van Vliet Huib A A M, Tchaikovski Svetlana N, Rosendaal Frits R, Rosing Jan, Helmerhorst Frans M

Abstract excerpt

Exogenously administered estrogens and progestogens as during combined oral contraceptive use increase the risk of venous thrombosis. The thrombin generation-based APC resistance assay is a global coagulation test that enables quantification of the net prothrombotic effect of combined oral contraceptives and that predicts the risk of thrombosis. The thrombotic risk of the levonorgestrel-releasing intrauterine...

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Source

Identifiers

PMID: 19350113

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The effect of the levonorgestrel-releasing intrauterine system on the resistance to activated protein C (APC).PMID 19350113Read ↗

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Changes of resistance to activated protein C in the course of pregnancy and prevalence of factor V mutation.Semantic proximity Read ↗

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