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Article

Altered dendritic cell phenotype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase, ERK.

The American journal of pathology - 1 May 2009

Boggiatto Paola Mercedes, Jie Fei, Ghosh Mousumi, Gibson-Corley Katherine Nicole, Ramer-Tait Amanda Ellen, Jones Douglas Elliot, Petersen Christine Anne

Abstract excerpt

Initiation of productive immune responses against Leishmania depends on the successful transition of dendritic cells (DC) from an immature to a mature phenotype. This process is characterized by high CD40 surface expression as well as interleukin-12 production, which are frequently seen in response to L. major infection. In vivo footpad infection of C3HeB/FeJ mice for 7 days with L. amazonensis promoted an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19349356
DOI: 10.2353/ajpath.2009.080905
PMCID: PMC2671270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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