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Article

Two waves of antigen‐containing dendritic cells <i>in vivo</i> in experimental <i>Leishmania major</i> infection

25 Feb 2004

Abstract excerpt

Dendritic cells (DC) can induce Th1 cell differentiation by producing IL-12. In experimental infection with Leishmania major, DC could differently respond to infection and induce Th1 cells in C57BL/6 but not BALB/c mice, and thus determine the resistance or susceptibility of these mice. We characterized L. major antigen-containing DC in vivo in draining lymph nodes of both strains. Conventional experimental...

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PMID: 14991601
DOI: 10.1002/eji.200324391

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