Theiler's virus infection induces a specific cytotoxic T lymphocyte response.

doi:10.1016/0008-8749(91)90158-8

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Article

Theiler's virus infection induces a specific cytotoxic T lymphocyte response.

Cellular immunology - 1 Dec 1991

Pena Rossi C, McAllister A, Fiette L, Brahic M

Abstract excerpt

Theiler's virus, a murine picornavirus, persists in the central nervous system of susceptible mouse strains and causes chronic inflammation and primary demyelination. One of the current hypotheses is that demyelination is, at least in part, mediated by virus-specific cytotoxic T lymphocytes (CTL)...

Topics

Animals
Enterovirus Infections
H-2 Antigens
Maus Elberfeld virus
Mice
Mice, Inbred BALB C
Mice, Inbred DBA
Phenotype
Plasmids
T-Lymphocytes, Cytotoxic
Transfection
Viral Proteins

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