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Article

A germ line mutation in exon 5 of the p53 gene in an extended cancer family.

Cancer research - 1 Dec 1991

Law J C, Strong L C, Chidambaram A, Ferrell R E

Abstract excerpt

Germ line p53 point mutations have been reported for some families with Li-Fraumeni syndrome, a syndrome characterized by a dominantly inherited increased susceptibility for the development of early age of onset neoplasms of diverse origin in multiple family members. All of the initially reported p53 germ line mutations have been found exclusively within a single conserved, nonpolymorphic region of the gene...

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PMID: 1933902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A germ line mutation in exon 5 of the p53 gene in an extended cancer family.PMID 1933902Read ↗

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