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Article

A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia

1 Apr 2009

Abstract excerpt

CONTEXT: Recent published studies indicate a possible role for sFlt1 in the development of preeclampsia. OBJECTIVE: The objective of the study was to investigate the expression and regulation of sFlt1-e15a, a recently described novel C-terminal variant isoform of sFlt1. DESIGN: The studies included a computational comparative analysis of the genomic locus of sFlt1 across vertebrate species; an assessment of sFlt1...

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Identifiers

PMID: 19336504
DOI: 10.1210/jc.2009-0017

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