Article
Pathogenesis of achalasia cardia.
World journal of gastroenterology - 28 Jun 2012
Ghoshal Uday C, Daschakraborty Sunil B, Singh Renu
Abstract excerpt
Achalasia cardia is one of the common causes of motor dysphagia. Though the disease was first described more than 300 years ago, exact pathogenesis of this condition still remains enigmatic. Pathophysiologically, achalasia cardia is caused by loss of inhibitory ganglion in the myenteric plexus of the esophagus. In the initial stage, degeneration of inhibitory nerves in the esophagus results in unopposed action of...
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