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Article

The role of T-cell immunoglobulin- and mucin-domain-containing molecule-3 polymorphisms in idiopathic thrombocytopenic purpura.

Human immunology - 1 Jun 2009

Du Wei Ting, Zhao Hai Feng, Xu Jian Hui, Gu Dong Sheng, Xue Feng, Ge Jing, Dong Xun Wei, Chen Zhen Ping, Zhou Ze Ping, Yang Ren Chi

Abstract excerpt

The family of T-cell immunoglobulin- and mucin-domain-containing molecules (TIMs) has an important role in immune regulation. TIM-3 is a transmembrane protein preferentially expressed on terminally differentiated Th1 cells and plays a role in T-helper (Th)-1-mediated autoimmune disease. Idiopathic thrombocytopenic purpura (ITP) is an acquired organ-specific autoimmune disease with a polarization of Th1. The...

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PMID: 19332093
DOI: 10.1016/j.humimm.2009.03.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The role of T-cell immunoglobulin- and mucin-domain-containing molecule-3 polymorphisms in idiopathic thrombocytopenic purpura.PMID 19332093Read ↗

Investigation of T-cell immunoglobulin- and mucin-domain-containing molecule-3 (TIM-3) polymorphisms in essential thrombocythaemia (ET).Semantic proximity Read ↗

[Linkage disequilibrium analysis of -1516, -574 and 4259 single nucleotide polymorphisms in TIM-3 gene].Semantic proximity Read ↗

Polymorphisms of the TIM-1 and TIM-3 genes are not associated with systemic lupus erythematosus in a Chinese population.Semantic proximity Read ↗

The +4259A>C polymorphism of TIM-3 but not -1637C>T polymorphism of TIM-1 is associated with Multiple sclerosis in Isfahan population.Semantic proximity Read ↗

Interferon-gamma +874A/T and interleukin-4 intron3 VNTR gene polymorphisms in Chinese patients with idiopathic thrombocytopenic purpura.Semantic proximity Read ↗

TIM-3 rs1036199 polymorphism increases susceptibility to autoimmune diseases: evidence based on 4200 subjectsSemantic proximity Read ↗

Molecular variations in Th1-specific cell surface gene Tim-3.Semantic proximity Read ↗

T cell immunoglobulin- and mucin-domain-containing molecule 3 gene polymorphisms and susceptibility to pancreatic cancer.Semantic proximity Read ↗

TIM-3 genetic variants and risk of Behçet disease in the Iranian population.Semantic proximity Read ↗

The polymorphisms of Th1 cell surface gene Tim-3 are associated in a Korean population with rheumatoid arthritis.Semantic proximity Read ↗

T Cell Immunoglobulin- and Mucin-Domain-Containing Molecule 3 Gene Polymorphisms and Susceptibility to Invasive Breast Cancer.Semantic proximity Read ↗

Association between gene polymorphisms and clinical features in idiopathic thrombocytopenic purpura patients.Semantic proximity Read ↗

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