Article
Cytotoxic T-lymphocyte antigen 4 gene polymorphisms are associated with latent autoimmune diabetes in adults.
Clinica chimica acta; international journal of clinical chemistry - 1 May 2009
Douroudis K, Prans E, Kisand K, Nemvalts V, Uibo R
Abstract excerpt
BACKGROUND: Cytotoxic T lymphocyte antigen-4 (CTLA-4) molecule is an important regulator of T cell activation involved in the down-regulation of immune response. Polymorphisms within the CTLA-4 gene have been suggested to confer susceptibility to autoimmune endocrine disorders. METHODS: In order...
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