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Article

Concurrent Hypermethylation of Multiple Genes Is Associated with Grade of Oligodendroglial Tumors

1 Aug 2001

Abstract excerpt

Current evidence suggests that epigenetic changes play an important role in the evolution of human cancers. In this study, we evaluated whether hypermethylation of CpG islands at the gene promotor regions of several tumor-related genes is involved in the carcinogenesis of oligodendroglial tumors. We examined the methylation status of 11 genes in a series of 43 oligodendroglial tumors (19 oligodendrogliomas, 13...

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PMID: 11487055
DOI: 10.1093/jnen/60.8.808

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Concurrent Hypermethylation of Multiple Genes Is Associated with Grade of Oligodendroglial TumorsPMID 11487055Read ↗

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