Article
Galectin-2 (LGALS2) 3279C/T polymorphism may be independently associated with diastolic blood pressure in patients with rheumatoid arthritis.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Apr 2009
Panoulas Vasileios F, Douglas Karen M J, Smith Jacqueline P, Metsios Georgios S, Elisaf Moses S, Nightingale Peter, Kitas George D
Abstract excerpt
The galectin-2 (LGALS2) 3279 C/T single nucleotide polymorphism (SNP) has recently been associated with myocardial infarction (MI). Although hypertension, a very prevalent entity in rheumatoid arthritis (RA), is one of the greatest risk factors for MI, the possible association of LGALS2 3279 C/T and hypertension has not been investigated. We genotyped 386 RA patients, 272 hypertensives and 114 normotensives....
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