Article
The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis.
Arthritis research & therapy - 1 Mar 2012
López-Mejías Raquel, González-Juanatey Carlos, García-Bermúdez Mercedes, Castañeda Santos, Miranda-Filloy José A, Blanco Ricardo, Llorca Javier, Martín Javier, González-Gay Miguel A
Abstract excerpt
INTRODUCTION: Rheumatoid arthritis (RA) is an inflammatory disease associated with accelerated atherosclerosis and high risk of cardiovascular (CV) disease. Since genome-wide association studies demonstrated association between rs599839 polymorphism and coronary artery disease, in the present study we assessed the potential association of this polymorphism with endothelial dysfunction, an early step in...
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