Article
Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.
Anesthesiology - 1 Apr 2009
Fox Amanda A, Collard Charles D, Shernan Stanton K, Seidman Christine E, Seidman Jonathan G, Liu Kuang-Yu, Muehlschlegel Jochen D, Perry Tjorvi E, Aranki Sary F, Lange Christoph, Herman Daniel S, Meitinger Thomas, Lichtner Peter, Body Simon C
Abstract excerpt
BACKGROUND: Ventricular dysfunction (VnD) after primary coronary artery bypass grafting is associated with increased hospital stay and mortality. Natriuretic peptides have compensatory vasodilatory, natriuretic, and paracrine influences on myocardial failure and ischemia. The authors hypothesized that natriuretic peptide system gene variants independently predict risk of VnD after primary coronary artery bypass...
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