5HT1Dbeta Receptor gene implicated in the pathogenesis of Obsessive-Compulsive Disorder: further evidence from a family-based association study.

doi:10.1038/sj.mp.4001059

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Article

5HT1Dbeta Receptor gene implicated in the pathogenesis of Obsessive-Compulsive Disorder: further evidence from a family-based association study.

Molecular psychiatry - 1 Jan 2002

Mundo E, Richter M A, Zai G, Sam F, McBride J, Macciardi F, Kennedy J L

Abstract excerpt

Obsessive-Compulsive Disorder (OCD) is a psychiatric condition with strong evidence for a genetic component and for the involvement of genes of the serotonin system. In a recent family-based association study we reported an association between the G allele of the G861C polymorphism of the 5HT1Dbeta receptor gene and OCD. The aim of the present study was to further investigate for the presence of linkage...

Topics

Family Health
Genotype
Humans
Linkage Disequilibrium
Obsessive-Compulsive Disorder
Receptor, Serotonin, 5-HT1D
Receptors, Serotonin

Source

Open in PubMed

Identifiers

PMID: 12192628
DOI: 10.1038/sj.mp.4001059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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