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Article

Plastin 1 binds to keratin and is required for terminal web assembly in the intestinal epithelium.

Molecular biology of the cell - 1 May 2009

Grimm-Günter Eva-Maria S, Revenu Céline, Ramos Sonia, Hurbain Ilse, Smyth Neil, Ferrary Evelyne, Louvard Daniel, Robine Sylvie, Rivero Francisco

Abstract excerpt

Plastin 1 (I-plastin, fimbrin) along with villin and espin is a prominent actin-bundling protein of the intestinal brush border microvilli. We demonstrate here that plastin 1 accumulates in the terminal web and interacts with keratin 19, possibly contributing to anchoring the rootlets to the keratin network. This prompted us to investigate the importance of plastin 1 in brush border assembly. Although in vivo...

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Identifiers

PMID: 19321664
DOI: 10.1091/mbc.e08-10-1030
PMCID: PMC2682596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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