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Gastrin‐releasing peptide: Different forms, different functions

1 Jan 2009

Abstract excerpt

All forms of the neuropeptide gastrin-releasing peptide (GRP) are derived from the precursor proGRP1-125. Amidated GRP18-27, which together with amidated GRP1-27 was long thought to be the only biologically relevant product of the GRP gene, is involved in a multitude of physiological functions and acts as a mitogen, morphogen, and proangiogenic factor in certain cancers. Recently, GRP has been implicated in...

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PMID: 19319848
DOI: 10.1002/biof.10

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