Article
Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility.
Cancer investigation - 1 Jul 2009
Springwald Anette, Lattrich Claus, Seitz Stephan, Ortmann Olaf, Treeck Oliver
Abstract excerpt
In this study, we tested the hypothesis that single nucleotide polymorphisms (SNPs) of differentiation-associated human gene icb-1 (C1orf38) may be associated with breast cancer susceptibility. A total of 646 women--323 breast cancer cases and just as many controls--were included. Breast cancer patients more frequently carried the homozygous genotype AA of SNP rs1467465 than did healthy women. Analysis of allele...
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