Article
The association between single-nucleotide polymorphisms of ORAI1 gene and breast cancer in a Taiwanese population.
TheScientificWorldJournal - 1 Jan 2012
Chang Wei-Chiao, Woon Peng Yeong, Hsu Yu-Wen, Yang Shengyu, Chiu Yi-Ching, Hou Ming Feng
Abstract excerpt
BACKGROUND: Breast cancer is the most common malignancy in women. There is increasing evidence suggesting that ORAI1, components of store-operated calcium channel, play a pivotal role in breast cancer progression and metastasis. METHODS: A total of 384 female patients with breast cancer were included in this study. We selected five representative tagging ORAI1 SNPs from HapMap database with minimum allele...
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