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Article

A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover.

The Journal of cell biology - 23 Mar 2009

Eastman Scott W, Yassaee Mina, Bieniasz Paul D

Abstract excerpt

HECT (homologous to the E6AP C terminus) ubiquitin ligases have diverse functions in eukaryotic cells. In screens for proteins that bind to the HECT ubiquitin ligase WWP1, we identified Spartin, which is also known as SPG20. This protein is truncated in a neurological disease, Troyer syndrome. In...

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Source

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Identifiers

PMID: 19307600
DOI: 10.1083/jcb.200808041
PMCID: PMC2699154

Genes

WWP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19307600-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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