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Article

Cytokine administration alters the distribution of activated lymphocytes to the lung.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1991

Dubinett S M, Callahan R J, Xia W J, Ahmad M, Strauss H W, Kradin R L

Abstract excerpt

The effects of intraperitoneal injections of recombinant interleukin-1 alpha (IL-1; 250,000 U/day), interleukin-2 (IL-2; 50,000 units/day), interferon-gamma (IFN-gamma; 50,000 U/day) and tumor necrosis factor-alpha (TNF; 100,000 U/day), on the biodistribution of concanavalin A (Con A)-activated, indium-111-labeled lymphocytes were evaluated in BALB/c mice. Syngeneic spleen cells were activated for 48 h in medium...

Topics

Animals
Cytokines
Female
Injections, Intraperitoneal
Interferon-gamma
Interleukin-1
Interleukin-2
Lung
Lymphocyte Activation
Lymphocytes
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Phenotype

Recombinant Proteins

Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 1930689
DOI: 10.1159/000163680

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1930689-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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