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Article

Combined skin and muscle vaccination differentially impact the quality of effector T cell functions: the CUTHIVAC-001 randomized trial

6 Oct 2017

Abstract excerpt

Targeting of different tissues via transcutaneous (TC), intradermal (ID) and intramuscular (IM) injection has the potential to tailor the immune response to DNA vaccination. In this Phase I randomised controlled clinical trial in HIV-1 negative volunteers we investigate whether the site and mode of DNA vaccination influences the quality of the cellular immune responses. We adopted a strategy of concurrent...

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PMID: 29026141
DOI: 10.1038/s41598-017-13331-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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