Article
Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease.
Journal of virology - 1 Jun 2009
Nedialkova Danny D, Ulferts Rachel, van den Born Erwin, Lauber Chris, Gorbalenya Alexander E, Ziebuhr John, Snijder Eric J
Abstract excerpt
Nidoviruses (arteriviruses, coronaviruses, and roniviruses) are a phylogenetically compact but diverse group of positive-strand RNA viruses that includes important human and animal pathogens. Nidovirus RNA synthesis is mediated by a cytoplasmic membrane-associated replication/transcription complex that includes up to 16 viral nonstructural proteins (nsps), which carry common enzymatic activities, like the viral...
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