Article
Domain Organization and Evolution of the Highly Divergent 5' Coding Region of Genomes of Arteriviruses, Including the Novel Possum Nidovirus.
Journal of virology - 15 Mar 2017
Gulyaeva Anastasia, Dunowska Magdalena, Hoogendoorn Erik, Giles Julia, Samborskiy Dmitry, Gorbalenya Alexander E
Abstract excerpt
In five experimentally characterized arterivirus species, the 5'-end genome coding region encodes the most divergent nonstructural proteins (nsp's), nsp1 and nsp2, which include papain-like proteases (PLPs) and other poorly characterized domains. These are involved in regulation of transcription, polyprotein processing, and virus-host interaction. Here we present results of a bioinformatics analysis of this...
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