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Article

Association of CRTH2 gene polymorphisms with the required dose of antihistamines in patients with chronic urticaria.

Pharmacogenomics - 1 Mar 2009

Palikhe Nami Shrestha, Kim Seung-Hyun, Ye Young-Min, Hur Gyu-Young, Cho Bo-Young, Park Hae-Sim

Abstract excerpt

INTRODUCTION: Chronic urticaria (CU), defined as the recurring incidence of wheals with or without angioedema for more than 6 weeks, is a common disorder associated with mast cell activation, degranulation, and histamine release. Considering the association between the CRTH2 gene and mast cells, we investigated the association of this gene polymorphism with the CU phenotype and antihistamine drug requirement in...

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Identifiers

PMID: 19290788
DOI: 10.2217/14622416.10.3.375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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