Article
Association of FCER1A genetic polymorphisms with risk for chronic spontaneous urticaria and efficacy of nonsedating H1-antihistamines in Chinese patients.
Archives of dermatological research - 1 Mar 2015
Guo Aiyuan, Zhu Wu, Zhang Chong, Wen Shu, Chen Xiaoping, Chen Mingliang, Zhang Jianglin, Su Juan, Chen Wangqing, Zhao Yue, Yan Siyu, He Yijing, Liu Zhaoqian, Zhou Honghao, Chen Xiang, Li Jie
Abstract excerpt
Antihistamines are the first-line treatment for chronic urticaria (CU). However, some CU patients are relatively refractory to antihistamines. The mechanism underlying the interindividual variation is still unknown. The α-chain of the high-affinity IgE receptor is crucial to the IgE-mediated allergic response. The present study is to investigate whether FCER1A polymorphisms are associated with the risk of CSU,...
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