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Article

Characterization and structural analysis of HIV-1 integrase conservation.

AIDS reviews - 1 Jan 2000

Ceccherini-Silberstein Francesca, Malet Isabelle, D'Arrigo Roberta, Antinori Andrea, Marcelin Anne-Genevieve, Perno Carlo-Federico

Abstract excerpt

The HIV-1 integrase, responsible for the chromosomal integration of the newly synthesized double-stranded viral DNA into the host genomic DNA, represents a new and important target of potential clinical relevance. For instance, two integrase inhibitors, raltegravir and elvitegravir, have been shown to be promising in clinical trials, and the first has been recently made available for clinical practice. As is the...

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Share to Conserved Sequence
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Structure, Tertiary

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PMID: 19290031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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