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Article

Effect of CYP2C9*3 allele on the pharmacokinetics of naproxen in Korean subjects.

Archives of pharmacal research - 1 Feb 2009

Bae Jung-Woo, Kim Ji-Hong, Choi Chang-Ik, Kim Mi-Jeong, Kim Hyung-Ji, Byun Seong-Ae, Chang Young-Soon, Jang Choon-Gon, Park Young-Seo, Lee Seok-Yong

Abstract excerpt

The genetically polymorphic CYP2C9 metabolizes many non-steroidal anti-inflammatory agents, including naproxen. This study examined the effects of a CYP2C9 genetic polymorphism on the pharmacokinetics of naproxen in Korean subjects. Twenty healthy male subjects carrying a CYP2C9*1/*1 (n=14) or CYP2C9*1/*3 (n=6) polymorphism were enrolled. After a single-dose of 275 mg naproxen Na, blood samples were collected at...

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Share to Anti-Inflammatory Agents, Non-Steroidal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aryl Hydrocarbon Hydroxylases

Share to Chromatography, High Pressure Liquid

Share to Cytochrome P-450 CYP2C9

Share to Polymorphism, Genetic

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Identifiers

PMID: 19280158
DOI: 10.1007/s12272-009-1232-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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