Role of functional single nucleotide polymorphisms of MMP1, MMP2, and MMP9 in open angle glaucomas.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Role of functional single nucleotide polymorphisms of MMP1, MMP2, and MMP9 in open angle glaucomas.

Molecular vision - 28 Aug 2010

Mossböck Georg, Weger Martin, Faschinger Christoph, Zimmermann Christine, Schmut Otto, Renner Wilfried, El-Shabrawi Yosuf

Abstract excerpt

PURPOSE: Matrix metalloproteinases (MMPs) play an essential role in the turnover of the extracellular matrix and cellular behavior. MMP1, MMP2, and MMP9 have previously been implicated in the pathogenesis of primary open angle glaucoma (POAG) and open angle glaucoma secondary to exfoliation syndrome (XFG), respectively. Functional gene polymorphisms of these MMPs such as MMP1 -1607 1G/2G (rs1799750), MMP2 -1306...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exfoliation Syndrome

Share to Glaucoma, Open-Angle

Share to Logistic Models

Share to Matrix Metalloproteinase 1

Share to Matrix Metalloproteinase 2

Share to Matrix Metalloproteinase 9

Share to Matrix Metalloproteinases

Source

Open in PubMed Open full text

Identifiers

PMID: 20808730
PMCID: PMC2929940

Genes

MMP2
MMP1
MMP9

Variants

rs1799750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of functional single nucleotide polymorphisms of MMP1, MMP2, and MMP9 in open angle glaucomas.PMID 20808730Read ↗

Novel Data about Association of the Functionally Significant Polymorphisms of the MMP9 Gene with Exfoliation Glaucoma in the Caucasian Population of Central Russia.Semantic proximity Read ↗

Evaluation of MMP1 and MMP3 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.Semantic proximity Read ↗

The Association of Single-Nucleotide Polymorphisms in the MMP-9 Gene with Normal Tension Glaucoma and Primary Open-Angle Glaucoma.Semantic proximity Read ↗

Functionally significant polymorphisms of the MMP9 gene are associated with primary open-angle glaucoma in the population of Russia.Semantic proximity Read ↗

Role of matrix metalloproteinase-9 gene polymorphisms in glaucoma: A hospital-based study in Chinese patients.Semantic proximity Read ↗

Matrix metalloproteinase-9 genetic variation and primary angle closure glaucoma in a Caucasian population.Semantic proximity Read ↗

The association of single nucleotide polymorphisms in the MMP-9 genes with susceptibility to acute primary angle closure glaucoma in Taiwanese patients.Semantic proximity Read ↗

Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma.Semantic proximity Read ↗

Matrix metalloproteinase-1 rs1799750 polymorphism and glaucoma: A meta-analysis.Semantic proximity Read ↗

Lack of association between the rs2664538 polymorphism in the MMP-9 gene and primary angle closure glaucoma in Singaporean subjects.Semantic proximity Read ↗

Gene polymorphisms of the MMP1, MMP9, MMP12, IL-1β and TIMP1 and the risk of primary open-angle glaucoma.Semantic proximity Read ↗

TNF-alpha -308 G>A and -238 G>A polymorphisms are not major risk factors in Caucasian patients with exfoliation glaucoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.