Article
Evaluation of MMP1 and MMP3 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
Molecular vision - 25 Dec 2009
Tsironi Evangelia E, Pefkianaki Maria, Tsezou Aspasia, Kotoula Maria G, Dardiotis Efthimios, Almpanidou Pavlina, Papathanasiou Afroditi A, Rodopoulou Paraskevi, Chatzoulis Dimitrios Z, Hadjigeorgiou Georgios M
Abstract excerpt
PURPOSE: To investigate possible genetic associations of matrix metalloproteinase-1 (MMP1) and MMP3 gene polymorphisms with exfoliation syndrome (XFS) with (XFS/+G) and without (XFS/-G) glaucoma in a cohort of Greek patients. METHODS: A total of 182 unrelated Greek patients with XFS, including 92 patients with XFS/+G, and 214 unrelated age- and gender-matched controls were enrolled in the study. MMP1 -1607 1G/2G...
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