Article
Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics.
Journal of cellular physiology - 1 Jul 2009
da Silva Cláudia Lobato, Gonçalves Raquel, Porada Christopher D, Ascensão João L, Zanjani Esmail D, Cabral Joaquim M S, Almeida-Porada Graça
Abstract excerpt
Human hematopoietic stem/progenitor cells (HSC) isolated based upon specific patterns of CD34 and CD38 expression, despite phenotypically identical, were found to be functionally heterogeneous, raising the possibility that reversible expression of these antigens may occur during cellular activation and/or proliferation. In these studies, we combined PKH67 tracking with CD34/CD38 immunostaining to compare cell...
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