Article
MYLK polymorphism associated with blood eosinophil level among asthmatic patients in a Korean population.
Molecules and cells - 28 Feb 2009
Lee Soo Ok, Cheong Hyun Sub, Park Byung Lae, Bae Joon Seol, Sim Won Chul, Chun Ji-Yong, Isbat Mohammad, Uh Soo-Taek, Kim Yong Hooun, Jang An-Soo, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
The myosin light chain kinase (MYLK) gene encodes both smooth muscle and nonmuscle cell isoforms. Recently, polymorphisms in MYLK have been reported to be associated with several diseases. To examine the genetic effects of polymorphisms on the risk of asthma and related phenotypes, we scrutinized MYLK by re-sequencing/genotyping and statistical analysis in Korean population (n = 1,015). Seventeen common...
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