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Article

Cholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb.

Molecular and cellular biology - 1 May 2009

Schmidt Katy, Hughes Catherine, Chudek J A, Goodyear Simon R, Aspden Richard M, Talbot Richard, Gundersen Thomas E, Blomhoff Rune, Henderson Colin, Wolf C Roland, Tickle Cheryll

Abstract excerpt

Cytochrome P450 oxidoreductase (POR) is the obligate electron donor for all microsomal cytochrome P450 enzymes, which catalyze the metabolism of a wide spectrum of xenobiotic and endobiotic compounds. Point mutations in POR have been found recently in patients with Antley-Bixler-like syndrome, wh...

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Identifiers

PMID: 19273610
DOI: 10.1128/MCB.01638-08
PMCID: PMC2682028

Genes

POR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19273610-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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