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Article

The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.

Molecular and cellular biology - 1 May 2009

Barkić Martina, Crnomarković Sladana, Grabusić Kristina, Bogetić Ivana, Panić Linda, Tamarut Sanda, Cokarić Maja, Jerić Ines, Vidak Sandra, Volarević Sinisa

Abstract excerpt

Hypomorphic mutation in one allele of ribosomal protein l24 gene (Rpl24) is responsible for the Belly Spot and Tail (Bst) mouse, which suffers from defects of the eye, skeleton, and coat pigmentation. It has been hypothesized that these pathological manifestations result exclusively from faulty protein synthesis. We demonstrate here that upregulation of the p53 tumor suppressor during the restricted period of...

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Identifiers

PMID: 19273598
DOI: 10.1128/MCB.01588-08
PMCID: PMC2682053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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