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In Vivo Role of Two-Component Regulatory Systems in Models of Urinary Tract Infections

10 Jan 2023

Abstract excerpt

Two-component signaling systems (TCSs) are finely regulated mechanisms by which bacteria adapt to environmental conditions by modifying the expression of target genes. In bacterial pathogenesis, TCSs play important roles in modulating adhesion to mucosal surfaces, resistance to antibiotics, and metabolic adaptation. In the context of urinary tract infections (UTI), one of the most common types infections causing...

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PMID: 36678467
DOI: 10.3390/pathogens12010119

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