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Article

Copy-number variation: the balance between gene dosage and expression in Drosophila melanogaster.

Genome biology and evolution - 1 Jan 2011

Zhou Jun, Lemos Bernardo, Dopman Erik B, Hartl Daniel L

Abstract excerpt

Copy-number variants (CNVs) reshape gene structure, modulate gene expression, and contribute to significant phenotypic variation. Previous studies have revealed CNV patterns in natural populations of Drosophila melanogaster and suggested that selection and mutational bias shape genomic patterns of CNV. Although previous CNV studies focused on heterogeneous strains, here, we established a number of...

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Identifiers

PMID: 21979154
DOI: 10.1093/gbe/evr023
PMCID: PMC3227403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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