Article
Cooperative interactions in the West Nile virus mutant swarm.
BMC evolutionary biology - 22 May 2012
Ciota Alexander T, Ehrbar Dylan J, Van Slyke Greta A, Willsey Graham G, Kramer Laura D
Abstract excerpt
BACKGROUND: RNA viruses including arthropod-borne viruses (arboviruses) exist as highly genetically diverse mutant swarms within individual hosts. A more complete understanding of the phenotypic correlates of these diverse swarms is needed in order to equate RNA swarm breadth and composition to specific adaptive and evolutionary outcomes. RESULTS: Here, we determined clonal fitness landscapes of mosquito...
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